China Vitae

Biography

Pei Gang, male, Han nationality, is a native of Shenyang, Liaoning Province. Pei graduated from Shenyang Pharmaceutical University in 1982 and received a master's degree from the institution 2 years later.

Pei mainly dealt with research on cell signal transducing and its regulating mechanism. He made use of G albumen coupling receptor variances and verified the hypothesis of receptor excitation balancing states. He found that the C end of the baica receptor (G albumen coupling) generates phosphorylation under the action of agonist and results in antianaphylaxis of the baica receptor. He revealed the important role of the baica receptor signal antianaphylaxis and negative feedback regulation in the formation of the baica habituation.

He also proved that there exists crosstalk between excited amino acid receptors and the baica receptors. He found that oxidated low-density lipoprotein can activate the p38MAPK through G albumen channels and restrains the growth of smooth muscle cells. Pei found that the TCM effective ingredient trichosanthis albumen can combine with HIV common receptors (chemotaxis factor receptor), strengthen the excitation of the receptors and thus bring anti-HIV into play. He also revealed that the chemotaxis factor receptor of the fifth span-membrane has the function of normal seventh span-membrane G albumen coupling receptor.