China Vitae

Biography

Zhang Yonglian, female, Han nationality, is a native of Shanghai. She graduated from Fudan University in 1957.

Zhang Yonglian participated in the early stages of scientific research of national defense and engaged in research on action principles of androgen. With respect to the mechanism research of prostate PSBP gene expression of androgen in induced big rats, she proved its function occurred on a duplicate level and identified 4 adjustment and control elements and its interactive reverse factor. She proposed combined with a special organization factor and provided evidence for the perspective of multiple elements and multiple factors participating cooperation. Zhang was one of the first scientists in this area.

Zhang also explained the time and spatial sequence of orphan nucleus receptor RTR expressions, completed a DNA clone and structure analysis of the 82Kb gene group, provided the possibility for a design of prophylactics by adjusting and controlling configuration changes of semen in the testicle.

Zhang broke into new gene research related to the maturation of semen in epididymis and obtained the whole cDNA of 13 new genes in monkeys and big rats. She discovered that one of the new genes of big rats, Bin1b, was not only related to bearing, but was also a natural antibiotic peptide and was the first gene discovered that was related to a special inherent defense system in epididymis.

Zhang is an academician of the Chinese Academy of Sciences.